Publications and Patents
Sumitha, N. S., Krishna, N. G., & Sailaja, G. S. *Multifunctional chitosan ferrogels for targeted cancer therapy by on-demand magnetically triggered drug delivery and hyperthermia. Biomaterials Advances, 142, 213137 (2022).
Arakkal, A., Sirajunnisa, P., & Sailaja, G. S. *Natural rubber latex films with effective growth inhibition against S. aureus via surface conjugated gentamicin. Journal of Bioactive and Compatible Polymers, 08839115231153823. (2023)
Sirajunnisa, P., Sabna, C., Aswin, A., Prathapan, S., & Sailaja, G. S. *Lawsone-bentonite hybrid systems for pH-dependent sustained release of ciprofloxacin. New Journal of Chemistry, 46(20), 9560-9571 (2022).
Nair, P.R., Sreeja.S& Sailaja, G.S.* Aqueous Ciss quadrangularis stem extract integrated biodegradable tissue engineering scaffold augment early biomimetic and biomineralization in vitro.Trends in Biomaterials and Artificial organs.
Arakkal, A., Rathinam, P., Sirajunnisa, P., Gopinathan, H., Vengellur, A., Bhat, S. G., & Sailaja, G. S. *Antibacterial natural rubber latex films with surface-anchored quaternary poly (4-vinyl pyridine) polyelectrolyte. Reactive and Functional Polymers, 172, 105190. (2022).
Nair, P. R., Sreeja, S. & Sailaja, G. S.*Cissus quadrangularis stem derived fiber: a natural osteoinductive substrate for regenerative bone tissue engineering. Cellulose 29, 413-426 (2022).
Conference Presentations (2022-23)
Aadithya Salbi, P. S. Sari, G. S. Sailaja, “Multifunctional Green Inorganic Template for Gold Nanoparticle based Nanotheranostic System for Targeted Cancer Treatment” 35th Kerala Science Congress- 2023, Mar Baselious Christian College of Engineering and Technology, Kuttikanam, Idukki (12th – 14th February 2023)
Sirajunnisa P and Sailaja G.S. Nanostructured Biocompatible Organobentonite based Hybrid material for Therapeutic Applications, International Conference on Sustainable Technology and Innovation for Industry 4.0, 2022
Sumitha N S, Nidhi G. Krishna., G. S Sailaja. Active On-Demand Doxorubicin Delivery by Magnetically Triggerable Chitosan Membranes for Customized Cancer Therapy, International conference on Sustainable technology and Innovation for Industry 4.0 (icstii 2022), 2022
Liz Hannah George, Prathapan S., and G. S. Sailaja, Bismuth based Radiopaque and Magnetic Nanotheranostic System for Cancer Therapy, NANOicon- January 2022
Liz Hannah George, Aswin Arakkal, Prathapan Sreedharan and G. S. Sailaja Injectable polyelectrolyte complex-nascent HAP biodegradable antibiotic delivery system for the treatment of osteomyelitis, Biomedical Materials, 2021, https://doi.org/10.1088/1748-605X/ac37c5
Praseetha R.Nair, S.Sreeja, and G.S.Sailaja*, Cissus quadrangularis stem derived fiber: a natural osteoinductive substrate for regenerative bone tissue engineering, Cellulose, 2021, https://doi.org/10.1007/s10570-021-04288-6
Praseetha R.Nair, S.Sreeja, and G.S.Sailaja*, Early biomineralizing chitosan–collagen hybrid scaffold with Cissus quadrangularis extract for regenerative bone tissue engineering, New Journal of Chemistry, 2021, DOI: 10.1039/d1nj03687d
K. R, S., P.S, S., & Sailaja, G. S. (2021). Intrinsically radiopaque and antimicrobial cellulose-based surgical sutures from mechanically empowered Agave sisalana plant leaf [10.1039/D1BM01316E]. Biomaterials Science. https://doi.org/10.1039/D1BM01316E
Nair, P., Sreeja, S., & Sailaja, G. S. (2021). Early biomineralizing chitosan-collagen hybrid scaffold with Cissus quadrangularis extract for regenerative bone tissue engineering. New Journal of Chemistry, In Press.
Sneha K.R and G.S. Sailaja, Intrinsically radiopaque biomaterial assortments: A short review on the physical principles, X-ray imageability and state-of-the-art developments, Journal of Materials Chemistry B, 13 September 2021,https://doi.org/10.1039/D1TB01513C
Praseetha R.Nair, S.Sreeja, and G.S.Sailaja, In vitro Biomineralization and Osteogenesis of Cissus quadrangularis Stem Extracts: An Osteogenic Regulator for Bone Tissue engineering, Journal of Biosciences, volume 46 (88) 2021, DOI:10.1007/s12038-021-00206-x.
N. S. Sumitha, S. Sreeja, P. J. George Varghese, G. S. Sailaja, A dual functional superparamagnetic system with pH-dependent drug release and hyperthermia potential for chemotherapeutic applications, Materials Chemistry and Physics
N. S. Sumitha, Prabha Prakash, Balagopal N. Nair, G. S. Sailaja, Degradation-Dependent Controlled Delivery of Doxorubicin by Glyoxal Cross-Linked Magnetic and Porous Chitosan Microspheres, ACS Omega, DOI: https://doi.org/10.1021/acsomega.1c02303
Irthasa Aazem, Prasanth Rathinam, Saju Pillai, Gopinathan Honey, Ajith Vengellur, Sarita G. Bhat, G. S. Sailaja, Active Bayerite Underpinned Ag2O/Ag: An Efficient Antibacterial Nanohybrid Combating Microbial Contamination, Metallomics, 2021 ( in press)
P. Sirajunnisa, Liz Hannah George, N. Manoj, S. Prathapan and G. S. Sailaja, Lawsone Derived Zn (II) and Fe (III) Metal-Organic Frameworks with pH-Dependent Emission for Controlled Drug Delivery, New Journal of Chemistry, 2021, DOI: 10.1039/D1NJ01913A
K.R. Sneha, S.Sreeja, G.S. Sailaja*, Radiopacity endowed magnetic nanocomposite with hyperthermia and in vitro mineralization potential: a combinatorial therapeutic system for osteosarcoma, Biomedical Materials, 2021 ( print)
K.R. Sneha, K. R. Sneha, Neenu Benny, Balagopal N. Nair, and G. S. Sailaja*, Natural Rubber Latex Assisted Shape-Attuned Synthesis of Intrinsically Radiopaque and Magnetic Bioceramic Nanocomposite with Hyperthermia Potential for Cancer Therapeutics, 2021, DOI: 10.1039/D1NJ01262B, New Journal of Chemistry, 2021
S. Sreeja, P. Ramesh, P. R. Harikrishna Varma, G.S. Sailaja*, Hierarchically porous osteoinductive Poly(hydroxyethyl methacrylate-co-methyl methacrylate) scaffold with sustained Doxorubicin delivery for consolidated osteosarcoma treatment and bone defect repair", ACS Biomaterials science and engineering, 2021, 7, 2, 701–717
Aswin A., Irthasa Aazem, Honey G. Ajith Vengellur, Sarita G.Bhat, and G.S. Sailaja*, Antibacterial Polyelectrolytic chitosan derivatives conjugated natural rubber latex films with minimized bacterial adhesion, J Appl Polym Sci, July 2020
K. Shijina, R. Ilathuvalappil, S. Nisa, G.S. Sailaja*, P. Mohamed, B.N.Nair, G.M.Anilkumar, K.Sreekumar, T.Yamaguchi and U.S.Hareesh, Fe3+ stabilized 3D cross-linked glycine-melamine formaldehyde networks as a precursor for highly efficient oxygen reduction catalyst in alkaline media, Materials Letters, Volume 264, April 2020, 127365
Praseetha R. Nair; G.S. Sailaja *. Biomimetic Bone grafts for Bone Tissue Engineering – From Concept to Design. Teresian International Journal of Chemical Science, 2020
Ananjana K, Swetha S, Prabha Prakash, Nishad T, Manoj Komath, B.N.Nair and G.S. Sailaja *., Amino acid inspired tunable superparamagnetic iron oxide (SPION) nanostructures with high magnetic hyperthermia potential for biofunctional applications, New Journal of Chemistry,2020, DOI: 10.1039/C9NJ05343C
S.Sreeja, C.V. Muraleedharan, P.R.H.K.Varma, G.S. Sailaja *, Surface transformed osteoinductive polyethylene terephthalate scaffold as a dual system for bone tissue regeneration, Materials Science and Engineering C, 109, 2020
S. Sasidharan, W, Naoto, G. M. Anilkumar, B. N. Balagopal, G. S. Sailaja, T. Takanori; T. Yamaguchi, Electro-oxidation competency of palladium nanocatalysts over ceria–carbon composite supports during alkaline ethylene glycol oxidation, Catalysis Science & Technology, 2018, 493-501
K. Shijina, R. Illathvalappil, N. S. Sumitha, G.S. Sailaja *, . Kurungot, B. N. Nair, A. P. Mohamed, G. M. Anilkumar, T. Yamaguchi, U. S. Hareesh, Melamine Formaldehyde - Metal-Organic Gel Interpenetrating Polymer Network Derived Intrinsic Fe-N- Doped Porous Graphitic Carbon Electrocatalysts for Oxygen Reduction Reaction, New Journal of Chemistry, 2018, 18690-18701
K. Shijina, R. Illathvalappil, S. Kurungot, B N. Nair, A. P.Mohamed, T Yamaguchi, G. M. Anilkumar, U. S. Hareesh, G.S. Sailaja *, Chitosan Intercalated Metal-Organic Gel as a Green Precursor of Fe Entrenched and Fe Distributed N-Doped Mesoporous Graphitic Carbon for Oxygen Reduction Reaction, Chemistry Select, 2017, 8762–8770
G.S. Sailaja *, P. Ramesh, Sajith Vellappally, Sukumaran Anil, H. K. Varma, Biomimetic approaches with smart interfaces for Bone regeneration, J Biomed Sci, 2016 Nov 5;23(1):77 (DOI: 10.1186/s12929-016-0284-x)
G. S. Sailaja, S. Miyanishi, T. Yamaguchi, A durable anion-conducting membrane with packed anion-exchange sites and an aromatic backbone for solid-state alkaline fuel cells, Polymer Chemistry, 2015,7964-7973
G. S. Sailaja, P. Zhang, G. M. Anilkumar, T. Yamaguchi, Anisotropically organized LDH on PVDF: A geometrically templated electrospun substrate for advanced anion conducting membranes, ACS Appl. Mater Interfaces, 2015, 7 (12), pp 6397-6401
G. S. Sailaja, Balagopal. N. Nair, Julian D. Gale, and Yamaguchi; Amino acid inspired microscale organization of metallic nanocrystals; J. Mater. Chem. A, 2014, 2, 100-106
G. S. Sailaja, Praveen Bhoopathi, Bharthi Gorantla, Chandramu Chetty, Venkateswara Rao Gogineni, Kiran Kumar Velpula, Christoper S. Gondi, J. S. Rao, The secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma, Int Journal of Oncology, 42(1), 2013,188-196
B.Gorantla, P. Bhoopathi, C. S. Gondi, G. S. Sailaja, J. S. RAO, Notch signaling regulates tumor-induced angiogenesis in SPARC - overexpressed neuroblastoma, Angiogenesis, 16(1), 2013, 85
G. S. Sailaja, P. Ramesh and H. K. Varma, Effect of surface functionalization on the physicomechanical properties of a novel biofunctional copolymer, J. Applied polymer science, 121(6), 2011, 3509-3511
G. S. Sailaja, P. Ramesh and H. K. Varma, Ultrastructural evaluation of in vitro in mineralized calcium phosphate phase on surface phosphorylated poly (hydroxyethyl meth acrylate-co-methyl methacrylate), Journal of Material science: Materials in Medicine, 21(4); 2010, 1183-1193.
G. S. Sailaja, M. Mohanty, P. V. Mohanan, T. V. Kumary, P. Ramesh, and H. K. Varma, Surface phosphorylated copolymer promotes direct bone bonding, Tissue Engineering Part A, 15(10); 2009, 3061-3069
G. S. Sailaja, K.Sreenivasan, Y.Yokogawa, T.V. Kumary, H K Varma, Bioinspired mineralization and cell adhesion on surface functionalized poly(vinyl alcohol) films, Acta Biomaterialia, 5(5) 2009, 1647-1655
G. S. Sailaja, P. Ramesh, H. K.Varma, Hydroxyapatite mouldable formulations using natural rubber latex as a binder, J Biomed Mater Res Part B, Appl Biomater, 82B, 2007, 231-238
G. S. Sailaja, P.Ramesh, T. V. Kumary, H. K. Varma, Human osteosarcoma cell adhesion behavior on hydroxyapatite integrated chitosan-poly(acrylic acid) polyelectrolyte complexes, Acta Biomaterialia, 2, 2006, 651-657(listed in top 25 hottest articles-2006)
G. S. Sailaja, T. V. Kumary, H. K. Varma, Biomimetically modified poly(2-hydroxy ethyl methacrylate-co-methyl methacrylate) microspheres for bone augmentation, Trends Biomater. Artif. Organs, 20, 2006, 3-6
G. S. Sailaja, T. V. Kumary, H. K. Varma, In vitro mineralization and cell adhesion on surface-modified poly(2-hydroxy ethyl methacrylate-co-methyl methacrylate), Key Eng Mater, 309, 2006, 493-496
G. S. Sailaja, P. Ramesh, H. K. Varma, Swelling behavior of hydroxyapatite filled chitosan-poly(acrylic polyelectrolyte complexes, J. Applied Polym Sci., 100, 2006, 4716-4722
G. S. Sailaja, S. Velayudhan, M. C. Sunny, K. Sreenivasan, H. K. Varma, P. Ramesh, Hydroxyapatite chitosan-poly(acrylic acid) polyelectrolyte complexes, J. Mater. Sci., 38, 2003
Patents - 10
1. A Radiopaque Brushite Bone Cement Formulation and Method of Preparation Thereof (G. S. Sailaja and Sneha K. R.; Indian patent- 202241031145; Filed 2022)
Porous Biodegradable Scaffolds for Regenerative Bone Tissue Engineering (G.S. Sailaja, Praseetha R.Nair, and S. Sreeja; Indian patent; 202141026897; Filed 2021)
A radiopaque surgical suture and method of preparation thereof. ( G.S. Sailaja and K.R. Sneha; Indian Patent: 202141026896; Filed 2021)
Natural Rubber Latex Compound With Layered Double Hydroxide Nano Gel Non-Black Reinforcing Filler ( G.S. Sailaja, Ananjana K., Irthasa azem Indian Patent; 202141030341; Filed 2021)
In situ exfoliated magnetic Layered double hydroxide (LDH) with enhanced magnetic hyperthermia potential for biomedical applications. (G.S. Sailaja, Ananjana K. Manoj Raama Varma; Indian Patent; 202041024102; Filed 2020)
Long-Lived Photoluminescent PMMA Silver Terephthalate Polymer Composite Films with antibacterial activity ( G.S.Sailaja; Liz Hannah George; Indian Patent; 202041003122; Filed 2020)
Anion conducting membrane from LDH ( G.M. Anilkumar, G.S.Sailaja, P.Zhang, T.Yamaguchi; Japanese Patent; 6243312; Granted 2017)
Silver nanoparticles and method of processing the same (Balagopal N. Nair and G.S. Sailaja; Japanese Patent; 5190420; Granted 2013)
Platinum nanoparticles and method of processing the same (Balagopal N. Nair and G.S. Sailaja; Japanese Patent; 5197518; Granted 2013)
Metallic nano-materials made from metallic nanoparticles and method of processing the same (Balagopal N. Nair and G.S. Sailaja; Japanese Patent; 5325037; Granted 2013)